Headlined by a Sept. 9 Super Bowl rematch between the Seahawks and Patriots, as well as the NFL’s first-ever game in Australia between the Rams and 49ers, Week 1 is absolutely loaded. Here are the lines for every Week 1 matchup at DraftKings Sportsbook as of Sept. 7. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. Patriots @ Seahawks Spread: Seahawks -3.5Moneyline: Seahawks -175, Patriots +145O/U: 44.5 49ers @ Rams (Australia) Spread: Rams -3.5Moneyline: Rams -185, 49ers +154O/U: 48.5 Saints @ Lions Spread: Lions -7Moneyline: Lions -305, Saints +245O/U: 49.5 Browns @ Jaguars Spread: Jaguars -8.5Moneyline: Jaguars -440, Browns +340O/U: 40.5 Bears @ Panthers Spread: Bears -3Moneyline: Bears -148, Panthers +124O/U: 46.5 Bills @ Texans Spread: Texans -1.5Moneyline: Texans -110, Texans -110O/U: 44.5 Ravens @ Colts Spread: Ravens -3.5Moneyline: Ravens -175, Colts +145O/U: 47.5 Buccaneers @ Bengals Spread: Bengals -3.5Moneyline: Bengals -205, Buccaneers +170O/U: 50.5 Falcons @ Steelers Spread: Steelers -3.5Moneyline: Steelers -180, Falcons +150O/U: 42.5 Jets @ Titans Spread: Titans -1.5Moneyline: Titans -125, Jets +105O/U: 39.5 Cardinals @ Chargers Spread: Chargers -10Moneyline: Chargers -500, Cardinals +380O/U: 47.5 Commanders @ Eagles Spread: Eagles -4.5Moneyline: Eagles -205, Commanders +170O/U: 44.5 Packers @ Vikings Spread: Vikings -1.5Moneyline: Vikings -122, Packers +102O/U: 46.5 Dolphins @ Raiders Spread: Raiders -3.5Moneyline: Raiders -185, Dolphins +154O/U: 40.5 Cowboys @ Giants Spread: Cowboys -3Moneyline: Cowboys -162, Giants +136O/U: 48.5 Broncos @ Chiefs Spread: Chiefs -3Moneyline: Chiefs -148, Broncos +124O/U: 43.5
2026 NFL Odds Week 1: Lines, Spreads For All 16 Games
